Purified Anti-Human CD49f Antibody[GoH3], Functional Grade (AN008930)
![Purified Anti-Human CD49f Antibody[GoH3], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Alternate Names | ITA, ITGA, Integrin alpha, Processed integrin alpha, alpha, VLA, CD49f, ITGA6B, VLA-6, Integrin alpha 6, ITGA6, alpha 6, Alpha6p, CD49 antigen-like family member F, Integrin, Integrin alpha6B, ITA6, Processed integrin alpha-6, VLA 6, &, alpha-6 integrin-n, VLA-6&, alpha |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelet cell |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee |
| Background | CD49f is a 120 kD integrin family member also known as VLA-6 α chain and α6 integrin subunit. CD49f associates with either integrin β1 (CD29) or integrin β4 (CD104) to form receptors (VLA-6 or α6β4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, and epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD49f protein |
| Abbre | CD49f |
| Swissprot | |
| Host | Rat |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3], Functional Grade |
| Applications |
FCM;Block
|
| Research Areas | Stem Cells;Signal Transduction;Developmental Biology;G protein signaling;PI3K-Akt Signaling Pathway;MAPK-Erk Signaling Pathway;Cytoskeleton;CDs;Embryonic Stem Cells;Hematopoietic Stem Cell Markers |
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Georas SN, et al. Blood. 1993 Oct;82(8):2872-8. |
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